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Medium RiskFDA Drug
Medications & Supplements/Prescription Drugs

Pfizer Inc.: Chantix (varenicline) Tablets Recalled for Impurity Above Safety Limits

Agency Publication Date: September 17, 2021
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Summary

Pfizer is voluntarily recalling several lots of Chantix (varenicline) 0.5 mg and 1 mg tablets because they were found to contain levels of N-nitroso-varenicline, a nitrosamine impurity, above the FDA's acceptable intake limit. This medication is used to help adults quit smoking and is distributed nationwide in various package sizes including 56-count bottles and blister packs. While no adverse events related to this specific impurity have been reported to date, Pfizer is recalling these specific lots as a precautionary measure to ensure consumer safety.

Risk

Long-term exposure to N-nitroso-varenicline above acceptable levels may increase the risk of cancer. This impurity belongs to a class of substances that are common in water and foods but are regulated in medications to prevent health risks from prolonged consumption.

What You Should Do

  1. Check your prescription bottle or carton for the brand name Chantix (varenicline) and match the NDC numbers: 00069-0471-03, 0069-0468-56, 0069-0469-56, or 0069-0469-03.
  2. Review the lot numbers and expiration dates on your packaging. Affected lots include 00018522, 00018523, 00018739, 00018740, 00020231, 00020232, 00020357, 00020358, 00020716, 00020813, 00021288, 00021289, 00021420, 00021687, 00021688, 00021788, 00021789, 00021790, 00021791, 00021792, 00022819, 00022851, 00023136, 00023137, 00023190, 00023448, DM0275, DM0276, DM0277, DY4470, EC5911, EC5912, ED6814, ET1600, ET1603, ET1607, ET1609, ET1611, CY6861, DM9007, DM9008, EN5725, EN8362, EN8467, 00018777, 00019289, 00019593, 00019682, 00019846, 00019977, 00020295, 00020448, 00020458, 00020480, 00021024, 00021073, 00021074, CW1565, CW1566, CW1567, CW1568, CW1569, CW1570, CW1571, CW1572, CW1573, CW1574, CW1575, CW1578, CW1579, CW1581, DF5277, DF5278, DF5279, DF5280, DF5281, DF5282, DR5086, DR5092, DR5093, DR5094, DT3885, DW4148, DW4152, DY7987, EC9841, EC9842, EC9847, EC9848, EE1011, EM1069, EM1070, EN5694, EN5695, EP1717, EP1718, EP1719, EW2012, EW3854, EW3865, EX2102, EX2103, 00019431, 00019542, 00019543, 00019544, 00020814, 00020815, 00020907, 00020965, 00021421, 00021422, 00021423, 00022136, 00022174, 00022175, 00022176, 00022177, 00022765, 00022766, 00023134, 00023135, 00023747, 00023748, DL3896, DL7779, DR2614, DX4576, DX5870, DX5871, DX5872, DX5873, DX7805, DY6078, DY7060, DY9367, DY9473, DY9475, DY9476, DY9505, EC5910, EC5913, EE9391, EF2346, EM4805, EM4807, EN2005, ET1601, ET1605, and ET1606.
  3. If you identify an affected lot, contact your healthcare provider or pharmacist for guidance on alternative treatments before stopping the medication, as the health benefits of quitting smoking may outweigh the risks of the impurity.
  4. Return any unused product from the recalled lots to your pharmacy for a refund and contact Pfizer at 1-800-438-1985 for further instructions.
  5. For additional information, contact the FDA Consumer Complaint hotline at 1-888-723-3332 (1-888-SAFEFDA) or visit www.fda.gov/safety/recalls.

Your Remedy Options

💰Full Refund

Refund and pharmaceutical guidance

How to: Contact your healthcare provider or pharmacist for guidance. Return any unused product to the pharmacy for a refund

Affected Products

Product: Chantix (varenicline) tablets 0.5mg/1mg (56 Tablets)
Model:
NDC 00069-0471-03
Lot Numbers:
00018522
00018523
00018739
00018740
00020231
00020232
00020357
00020358
00020716
00020813
00021288
00021289
00021420
00021687
00021688
00021788
00021789
00021790
00021791
00021792
00022819
00022851
00023136
00023137
00023190
00023448
DM0275
DM0276
DM0277
DY4470
EC5911
EC5912
ED6814
ET1600
ET1603
ET1607
ET1609
ET1611
Date Ranges: August 2021 - January 2023
Product: Chantix (varenicline) tablets 0.5mg (56 Tablets)
Model:
NDC 0069-0468-56
Lot Numbers:
CY6861
DM9007
DM9008
EN5725
EN8362
EN8467
Date Ranges: January 2022 - May 2023
Product: Chantix (varenicline) tablets 1 mg (56 Tablets)
Model:
NDC 0069-0469-56
Lot Numbers (58):
00018777
00019289
00019593
00019682
00019846
00019977
00020295
00020448
00020458
00020480
00021024
00021073
00021074
CW1565
CW1566
CW1567
CW1568
CW1569
CW1570
CW1571
CW1572
CW1573
CW1574
CW1575
CW1578
CW1579
CW1581
DF5277
DF5278
DF5279
DF5280
DF5281
DF5282
DR5086
DR5092
DR5093
DR5094
DT3885
DW4148
DW4152
DY7987
EC9841
EC9842
EC9847
EC9848
EE1011
EM1069
EM1070
EN5694
EN5695
Date Ranges: September 2021 - December 2023
Product: Chantix (varenicline) tablets 1 mg (Carton of 4 blister packs/14 tablets each)
Model:
NDC 0069-0469-03
Lot Numbers:
00019431
00019542
00019543
00019544
00020814
00020815
00020907
00020965
00021421
00021422
00021423
00022136
00022174
00022175
00022176
00022177
00022765
00022766
00023134
00023135
00023747
00023748
DL3896
DL7779
DR2614
DX4576
DX5870
DX5871
DX5872
DX5873
DX7805
DY6078
DY7060
DY9367
DY9473
DY9475
DY9476
DY9505
EC5910
EC5913
EE9391
EF2346
EM4805
EM4807
EN2005
ET1601
ET1605
ET1606
Date Ranges: September 2021 - December 2023, September 2021 - June 2023

Additional Information

Agency: Food and Drug Administration (FDA)
Event ID: 88497
Status: Active
Manufacturer: Pfizer Inc.
Sold By: Pfizer Labs; Pharmacies
Manufactured In: Ireland
Distributed To: Nationwide

Were You Affected by This Recall?

If you or a family member were harmed by this recalled product, you may have legal rights. Consider consulting a consumer protection attorney to understand your options for compensation.

Find an Attorney

This is general information, not legal advice. Go Backs is not a law firm and does not provide legal services.

AI-Enhanced Content: The summary, action steps, and risk assessment on this page were generated by AI from official government recall data to improve readability. This is not legal or medical advice. Always refer to the official agency sources below for authoritative information.

Sources: FDA iRES · Raw API Response

openFDA Disclaimer: This recall information is sourced from the openFDA API. Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. Refer to the openFDA terms of service for more information.