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Recall data is sourced from official U.S. government agencies (CPSC, FDA, NHTSA, USDA) and processed using AI to improve readability. This site is not affiliated with or endorsed by any government agency. Always refer to the original agency notice for authoritative information.

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Medium RiskFDA Drug
Medications & Supplements/Prescription Drugs

Mylan Laboratories Limited, (Nashik FDF): Valsartan and Amlodipine Heart Medications Recalled for NDEA Impurity

Agency Publication Date: December 12, 2018
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Summary

Approximately 1,211,626 bottles of various blood pressure medications, including Valsartan and Amlodipine/Valsartan combinations, have been recalled because they contain trace amounts of N-nitrosodiethylamine (NDEA). This impurity was found in the active pharmaceutical ingredient (API) used to manufacture these drugs in India. The recall affects several strengths and bottle sizes of Mylan Pharmaceuticals products distributed across the United States and Puerto Rico.

Risk

NDEA is a substance that occurs naturally in certain foods and drinking water, but it is classified as a probable human carcinogen. While trace amounts were found, long-term exposure to this impurity above acceptable levels may increase the risk of cancer.

What You Should Do

  1. Check the label of your prescription bottle for the manufacturer 'Mylan Pharmaceuticals' and the NDC numbers including 0378-1721-93, 0378-1722-93, 0378-1723-93, 0378-1724-93, 0378-5807-93, 0378-5813-77, 0378-5814-77, 0378-5815-77, 0378-6321-77, 0378-6321-05, 0378-6322-77, 0378-6322-05, 0378-6323-77, 0378-6323-05, 0378-6324-77, 0378-6324-05, 0378-6325-77, and 0378-6325-05.
  2. Verify if your bottle matches one of the affected lot numbers, such as 3064084, 3069629, 3073148, 3073149, 3076093, 3077772, 3064085, 3066063, 3069638, 3069639, 3064086, 3066061, 3066062, 3073145, 3073146, 3073147, 3076091, 3077619, 3082432, 3066064, 3069645, 3069646, 3073142, 3073143, 3073144, 3077617, 3063780, 3074879, 3086684, 3086687, 3065445, 3074880, 3074883, 3086688, 3086689, 3086710, 3069019, 3069020, 3069021, 3069022, 3071354, 3071355, 3071357, 3079023, 3079027, 3079028, 3079029, 3079996, 3079997, 3079998, 3083635, 3086715, 3086716, 3086717, 3088623, 3063783, 3063784, 3063785, 3064092, 3064093, 3064094, 3070349, 3070350, 3070351, 3070352, 3070353, 3070354, 3079030, 3079031, 3079032, 3079033, 3080011, 3080224, 3081498, 3081500, 3087126, 3088476, 3084363, 3084364, 3093800, 2008880, 3084358, 3084359, 3084361, 3093801, 3084887, 3084888, 3093802, 3084889, 3084890, 3093803, 3084860, 3084861, 3084862, 3084863, and 3093804.
  3. Do NOT stop taking your medication before talking to your doctor or pharmacist, as stopping blood pressure medication abruptly can pose immediate health risks.
  4. Contact your healthcare provider or pharmacist for guidance on obtaining a replacement or alternative treatment.
  5. Return any unused product from the affected lots to your pharmacy for a refund.
  6. For additional questions, contact the FDA Consumer Complaint hotline at 1-888-723-3332 (1-888-SAFEFDA) or visit www.fda.gov/safety/recalls.

Your Remedy Options

💰Full Refund

Contact your healthcare provider or pharmacist for guidance. Return any unused product to the pharmacy for a refund

How to: Contact your healthcare provider or pharmacist for guidance. Return any unused product to the pharmacy for a refund

Affected Products

Product: Amlodipine and Valsartan Tablets, USP 5/160 mg (30-count bottle)
Model:
NDC 0378-1721-93
Lot Numbers:
3064084
3069629
3073148
3073149
3076093
3077772
Product: Amlodipine and Valsartan Tablets, USP 10/160 mg (30-count bottle)
Model:
NDC 0378-1722-93
Lot Numbers:
3064085
3066063
3069638
3069639
Product: Amlodipine and Valsartan Tablets, USP 5/320 mg (30-count bottle)
Model:
NDC 0378-1723-93
Lot Numbers:
3064086
3066061
3066062
3073145
3073146
3073147
3076091
3077619
3082432
Product: Amlodipine and Valsartan Tablets, USP 10/320 mg (30-count bottle)
Model:
NDC 0378-1724-93
Lot Numbers:
3066064
3069645
3069646
3073142
3073143
3073144
3077617
Product: Valsartan Tablets, USP 40 mg (30-count bottle)
Model:
NDC 0378-5807-93
Lot Numbers:
3063780
3074879
3086684
3086687
Product: Valsartan Tablets, USP 80 mg (90-count bottle)
Model:
NDC 0378-5813-77
Lot Numbers:
3065445
3074880
3074883
3086688
3086689
3086710
Product: Valsartan Tablets, USP 160 mg (90-count bottle)
Model:
NDC 0378-5814-77
Lot Numbers:
3069019
3069020
3069021
3069022
3071354
3071355
3071357
3079023
3079027
3079028
3079029
3079996
3079997
3079998
3083635
3086715
3086716
3086717
3088623
Product: Valsartan Tablets, USP 320 mg (90-count bottle)
Model:
NDC 0378-5815-77
Lot Numbers:
3063783
3063784
3063785
3064092
3064093
3064094
3070349
3070350
3070351
3070352
3070353
3070354
3079030
3079031
3079032
3079033
3080011
3080224
3081498
3081500
3087126
3088476
Product: Valsartan and Hydrochlorothiazide Tablets, USP 80/12.5 mg (90 or 500-count bottle)
Model:
NDC 0378-6321-77
NDC 0378-6321-05
Lot Numbers:
3084363
3084364
3093800
Product: Valsartan and Hydrochlorothiazide Tablets, USP 160/12.5 mg (90 or 500-count bottle)
Model:
NDC 0378-6322-77
NDC 0378-6322-05
Lot Numbers:
2008880
3084358
3084359
3084361
3093801
Product: Valsartan and Hydrochlorothiazide Tablets, USP 160/25 mg (90 or 500-count bottle)
Model:
NDC 0378-6323-77
NDC 0378-6323-05
Lot Numbers:
3084887
3084888
3093802
Product: Valsartan and Hydrochlorothiazide Tablets, USP 320/12.5 mg (90 or 500-count bottle)
Model:
NDC 0378-6324-77
NDC 0378-6324-05
Lot Numbers:
3084889
3084890
3093803
Product: Valsartan and Hydrochlorothiazide Tablets, USP 320/25 mg (90 or 500-count bottle)
Model:
NDC 0378-6325-77
NDC 0378-6325-05
Lot Numbers:
3084860
3084861
3084862
3084863
3093804

Additional Information

Agency: Food and Drug Administration (FDA)
Event ID: 81707
Status: Active
Manufacturer: Mylan Laboratories Limited, (Nashik FDF)
Sold By: major distributors
Manufactured In: India
Units Affected: 13 products (141,995 HDPE bottles; 76,516 HDPE bottles; 109,314 HDPE bottles; 84,066 HDPE bottles; 160,300 HDPE bottles; 119,761 HDPE bottles; 232,180 HDPE bottles; 129,754 HDPE bottles; 32,696 HDPE bottles; 50,595 HDPE bottles; 22,813 HDPE bottles; 19,352 HDPE bottles; 32,284 HDPE bottles)
Distributed To: Nationwide
Agency Last Updated: December 26, 2018

Were You Affected by This Recall?

If you or a family member were harmed by this recalled product, you may have legal rights. Consider consulting a consumer protection attorney to understand your options for compensation.

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This is general information, not legal advice. Go Backs is not a law firm and does not provide legal services.

AI-Enhanced Content: The summary, action steps, and risk assessment on this page were generated by AI from official government recall data to improve readability. This is not legal or medical advice. Always refer to the official agency sources below for authoritative information.

Sources: FDA iRES · Raw API Response

openFDA Disclaimer: This recall information is sourced from the openFDA API. Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. Refer to the openFDA terms of service for more information.